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A new weight-loss drug which contains anti-addiction drug naltrexone has become approved by the U.S. Food and Drug Administration today, the business said in a statement.

Using two separate drugs to lose weight can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you ought to err on the side of caution and let the FDA do its job and demand some investigation be done so the public knows the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on their medications.

Researchers discovered that participants taking this drug for the year, dropped excess weight within 4 weeks and have kept the weight off through the entire 56 weeks from the study. Contrave is often a combination of the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which can be made up of several active ingredient, which might make them more efficient and safer.

Combo-pilling will be the newest fad or even better the newest to come under scrutiny and for that reason it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular is the fact that at the time of right now there are no long term prescription diet pills that have been approved by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures really are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug can also raise blood pressure and heartbeat, and really should not be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise hypertension and heart rate and must not be used in patients with uncontrolled high blood pressure level, as well as by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients towards the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.


Suboxone includes two drugs; buprenorphine and naloxone. The naloxone is irrelevant if your addict uses the medication properly, but in the event the tablet is dissolved in water and injected the naloxone will cause instant withdrawal. When suboxone is utilized correctly, the naloxone is destroyed in the liver after that uptake in the intestines and possesses no therapeutic effect. Buprenorphine is the active substance; it can be absorbed under the tongue (and through the mouth) but destroyed through the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I purchased this formulation in the event the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I have treated addicts who may have had gastric bypass, the location where the first part of the intestine is bypassed and also the stomach contents empty in a more distal area of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the process with normal anatomy the location where the drug is taken up with the duodenum and transferred straight away to the liver from the portal vein, where it is quickly and completely destroyed. After gastric bypass naloxone can be taken up by servings of the intestine which are not served with the portal system, causing blood degrees of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.